Matt Iseman is a comedian, and television host best known for his 17-season tenure as the voice of American Ninja Warrior. A graduate of Princeton University and Columbia University’s College of Physicians and Surgeons, he transitioned from a career in medicine to entertainment, eventually winning The New Celebrity Apprentice and raising nearly $1 million for charity. He is an Emmy Award-winning host whose credits include Live Rescue, Clean House, and numerous specials for the History Channel and A&E.
As a survivor of both cancer and Rheumatoid Arthritis, Matt is a prominent health advocate and a national spokesperson for the Arthritis Foundation. He uses his platform to share his personal journey with chronic illness, focusing on the importance of resilience and physical activity. Now serving as an ambassador for the 2026 Special Olympics USA Games, Matt combines his medical background and his experience celebrating elite athletes to champion inclusion. He is dedicated to highlighting the stories of Special Olympics athletes and supporting a culture where every competitor can showcase their strength and determination.